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dnase i–hypersensitive site sequencing (dnase-seq) data bigwig files  (Santa Cruz Biotechnology)


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    Santa Cruz Biotechnology dnase i–hypersensitive site sequencing (dnase-seq) data bigwig files
    Genetic mapping and epigenetic landscape of the 13q12.2 locus. Map of the FLT3 and PAN3 loci in 13q12.2. Predicted topologically associating domains based on data from the lymphoblastic GM12878 cell line are indicated by diagonal dashed lines. (A) Hemizygous deletions identified in 27 BCP ALL samples by WGS (black) or SNP array or WES (gray). The violet square corresponds to the minimally deleted region. (B) <t>DNase-seq</t> signal based on the GM12878 cell line. (C) ATAC-seq signal based on the NALM-6 cell line. (D) ChIP-seq of histone modifications (H3K27ac and H3K4me3) based on the GM12878 (E) and the NALM-6 cell lines. (F) H3K27ac- and H3K4me3-enriched PLAC-seq interaction map based on the NALM-6 cell line. (G) Relative interaction frequencies in 13q12.2 in 6 primary ALL cases and the GM12878 cell line based on Hi-C, where higher values on the y-axis correspond to stronger interaction. Increased interactions with the enhancer element DS3 are seen in the case with 13q12.2 deletion.
    Dnase I–Hypersensitive Site Sequencing (Dnase Seq) Data Bigwig Files, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/dnase+i%E2%80%93hypersensitive+site+sequencing+(dnase-seq)+data+bigwig+files/dnase+i+hypersensitive+site+sequencing++dnase+seq++data+bigwig+files/pmc07498303-118-18-33
    Average 90 stars, based on 1 article reviews
    dnase i–hypersensitive site sequencing (dnase-seq) data bigwig files - by Bioz Stars, 2026-09
    90/100 stars

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    1) Product Images from "13q12.2 deletions in acute lymphoblastic leukemia lead to upregulation of FLT3 through enhancer hijacking"

    Article Title: 13q12.2 deletions in acute lymphoblastic leukemia lead to upregulation of FLT3 through enhancer hijacking

    Journal: Blood

    doi: 10.1182/blood.2019004684

    Genetic mapping and epigenetic landscape of the 13q12.2 locus. Map of the FLT3 and PAN3 loci in 13q12.2. Predicted topologically associating domains based on data from the lymphoblastic GM12878 cell line are indicated by diagonal dashed lines. (A) Hemizygous deletions identified in 27 BCP ALL samples by WGS (black) or SNP array or WES (gray). The violet square corresponds to the minimally deleted region. (B) DNase-seq signal based on the GM12878 cell line. (C) ATAC-seq signal based on the NALM-6 cell line. (D) ChIP-seq of histone modifications (H3K27ac and H3K4me3) based on the GM12878 (E) and the NALM-6 cell lines. (F) H3K27ac- and H3K4me3-enriched PLAC-seq interaction map based on the NALM-6 cell line. (G) Relative interaction frequencies in 13q12.2 in 6 primary ALL cases and the GM12878 cell line based on Hi-C, where higher values on the y-axis correspond to stronger interaction. Increased interactions with the enhancer element DS3 are seen in the case with 13q12.2 deletion.
    Figure Legend Snippet: Genetic mapping and epigenetic landscape of the 13q12.2 locus. Map of the FLT3 and PAN3 loci in 13q12.2. Predicted topologically associating domains based on data from the lymphoblastic GM12878 cell line are indicated by diagonal dashed lines. (A) Hemizygous deletions identified in 27 BCP ALL samples by WGS (black) or SNP array or WES (gray). The violet square corresponds to the minimally deleted region. (B) DNase-seq signal based on the GM12878 cell line. (C) ATAC-seq signal based on the NALM-6 cell line. (D) ChIP-seq of histone modifications (H3K27ac and H3K4me3) based on the GM12878 (E) and the NALM-6 cell lines. (F) H3K27ac- and H3K4me3-enriched PLAC-seq interaction map based on the NALM-6 cell line. (G) Relative interaction frequencies in 13q12.2 in 6 primary ALL cases and the GM12878 cell line based on Hi-C, where higher values on the y-axis correspond to stronger interaction. Increased interactions with the enhancer element DS3 are seen in the case with 13q12.2 deletion.

    Techniques Used: ChIP-sequencing, Hi-C

    Related Articles

    Chromatin Immunoprecipitation:

    Article Title: 13q12.2 deletions in acute lymphoblastic leukemia lead to upregulation of FLT3 through enhancer hijacking
    Article Snippet: Chromatin structure and ChIP-seq data mining GM12878 histone marks chromatin immunoprecipitation (ChIP)-sequencing (ChIP-seq) data (H3K27ac and H3K4me3) and DNase I–hypersensitive site sequencing (DNase-seq) data (bigwig files) were downloaded from the University of California, Santa Cruz (UCSC) database ( http://genome.ucsc.edu/ENCODE/dataMatrix/encodeDataMatrixHuman.html ).

    Sequencing:

    Article Title: 13q12.2 deletions in acute lymphoblastic leukemia lead to upregulation of FLT3 through enhancer hijacking
    Article Snippet: Chromatin structure and ChIP-seq data mining GM12878 histone marks chromatin immunoprecipitation (ChIP)-sequencing (ChIP-seq) data (H3K27ac and H3K4me3) and DNase I–hypersensitive site sequencing (DNase-seq) data (bigwig files) were downloaded from the University of California, Santa Cruz (UCSC) database ( http://genome.ucsc.edu/ENCODE/dataMatrix/encodeDataMatrixHuman.html ).

    ChIP-sequencing:

    Article Title: 13q12.2 deletions in acute lymphoblastic leukemia lead to upregulation of FLT3 through enhancer hijacking
    Article Snippet: Chromatin structure and ChIP-seq data mining GM12878 histone marks chromatin immunoprecipitation (ChIP)-sequencing (ChIP-seq) data (H3K27ac and H3K4me3) and DNase I–hypersensitive site sequencing (DNase-seq) data (bigwig files) were downloaded from the University of California, Santa Cruz (UCSC) database ( http://genome.ucsc.edu/ENCODE/dataMatrix/encodeDataMatrixHuman.html ).

    Hi-C:

    Article Title: 13q12.2 deletions in acute lymphoblastic leukemia lead to upregulation of FLT3 through enhancer hijacking
    Article Snippet: Chromatin structure and ChIP-seq data mining GM12878 histone marks chromatin immunoprecipitation (ChIP)-sequencing (ChIP-seq) data (H3K27ac and H3K4me3) and DNase I–hypersensitive site sequencing (DNase-seq) data (bigwig files) were downloaded from the University of California, Santa Cruz (UCSC) database ( http://genome.ucsc.edu/ENCODE/dataMatrix/encodeDataMatrixHuman.html ).



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    dnase i–hypersensitive site sequencing (dnase-seq) data bigwig files  (Santa Cruz Biotechnology)
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    Santa Cruz Biotechnology dnase i–hypersensitive site sequencing (dnase-seq) data bigwig files
    Genetic mapping and epigenetic landscape of the 13q12.2 locus. Map of the FLT3 and PAN3 loci in 13q12.2. Predicted topologically associating domains based on data from the lymphoblastic GM12878 cell line are indicated by diagonal dashed lines. (A) Hemizygous deletions identified in 27 BCP ALL samples by WGS (black) or SNP array or WES (gray). The violet square corresponds to the minimally deleted region. (B) <t>DNase-seq</t> signal based on the GM12878 cell line. (C) ATAC-seq signal based on the NALM-6 cell line. (D) ChIP-seq of histone modifications (H3K27ac and H3K4me3) based on the GM12878 (E) and the NALM-6 cell lines. (F) H3K27ac- and H3K4me3-enriched PLAC-seq interaction map based on the NALM-6 cell line. (G) Relative interaction frequencies in 13q12.2 in 6 primary ALL cases and the GM12878 cell line based on Hi-C, where higher values on the y-axis correspond to stronger interaction. Increased interactions with the enhancer element DS3 are seen in the case with 13q12.2 deletion.
    Dnase I–Hypersensitive Site Sequencing (Dnase Seq) Data Bigwig Files, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/dnase+i%E2%80%93hypersensitive+site+sequencing+(dnase-seq)+data+bigwig+files/dnase+i+hypersensitive+site+sequencing++dnase+seq++data+bigwig+files/pmc07498303-118-18-33
    Average 90 stars, based on 1 article reviews
    dnase i–hypersensitive site sequencing (dnase-seq) data bigwig files - by Bioz Stars, 2026-09
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    Genetic mapping and epigenetic landscape of the 13q12.2 locus. Map of the FLT3 and PAN3 loci in 13q12.2. Predicted topologically associating domains based on data from the lymphoblastic GM12878 cell line are indicated by diagonal dashed lines. (A) Hemizygous deletions identified in 27 BCP ALL samples by WGS (black) or SNP array or WES (gray). The violet square corresponds to the minimally deleted region. (B) DNase-seq signal based on the GM12878 cell line. (C) ATAC-seq signal based on the NALM-6 cell line. (D) ChIP-seq of histone modifications (H3K27ac and H3K4me3) based on the GM12878 (E) and the NALM-6 cell lines. (F) H3K27ac- and H3K4me3-enriched PLAC-seq interaction map based on the NALM-6 cell line. (G) Relative interaction frequencies in 13q12.2 in 6 primary ALL cases and the GM12878 cell line based on Hi-C, where higher values on the y-axis correspond to stronger interaction. Increased interactions with the enhancer element DS3 are seen in the case with 13q12.2 deletion.

    Journal: Blood

    Article Title: 13q12.2 deletions in acute lymphoblastic leukemia lead to upregulation of FLT3 through enhancer hijacking

    doi: 10.1182/blood.2019004684

    Figure Lengend Snippet: Genetic mapping and epigenetic landscape of the 13q12.2 locus. Map of the FLT3 and PAN3 loci in 13q12.2. Predicted topologically associating domains based on data from the lymphoblastic GM12878 cell line are indicated by diagonal dashed lines. (A) Hemizygous deletions identified in 27 BCP ALL samples by WGS (black) or SNP array or WES (gray). The violet square corresponds to the minimally deleted region. (B) DNase-seq signal based on the GM12878 cell line. (C) ATAC-seq signal based on the NALM-6 cell line. (D) ChIP-seq of histone modifications (H3K27ac and H3K4me3) based on the GM12878 (E) and the NALM-6 cell lines. (F) H3K27ac- and H3K4me3-enriched PLAC-seq interaction map based on the NALM-6 cell line. (G) Relative interaction frequencies in 13q12.2 in 6 primary ALL cases and the GM12878 cell line based on Hi-C, where higher values on the y-axis correspond to stronger interaction. Increased interactions with the enhancer element DS3 are seen in the case with 13q12.2 deletion.

    Article Snippet: Chromatin structure and ChIP-seq data mining GM12878 histone marks chromatin immunoprecipitation (ChIP)-sequencing (ChIP-seq) data (H3K27ac and H3K4me3) and DNase I–hypersensitive site sequencing (DNase-seq) data (bigwig files) were downloaded from the University of California, Santa Cruz (UCSC) database ( http://genome.ucsc.edu/ENCODE/dataMatrix/encodeDataMatrixHuman.html ).

    Techniques: ChIP-sequencing, Hi-C